We investigate biomolecular interactions, down to the single molecule level.


Our interdisciplinary group uses approaches from biophysics, biochemistry, cell and molecular biology, analytical and physical chemistry, optics and materials science to answer questions about how molecules (proteins, lipids) interact with each other to effect functional biological responses.  The systems we investigate include immunoreceptor signaling for the allergic response, macromolecular crowding, biomembranes and biosensors.  We use fluorescence microscopy and spectroscopy and optical trapping to measure and manipulate these single molecule interactions in live cells and biomimetic systems.  



Find out more about some research projects we are currently working on.

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